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type=\"disc\">\n<li><b>\u751f\u5b58\u83b7\u76ca<\/b>\uff1a\u5bf9\u4e8ePD-L1\u9633\u6027\u4eba\u7fa4\uff0c\u8054\u5408\u6cbb\u7597\u7ec4\u4e2d\u4f4dOS\u8fbe35.8\u4e2a\u6708\uff0c\u8fdc\u8d85\u5316\u7597\u7ec4\u768423.6\u4e2a\u6708\uff0c\u6b7b\u4ea1\u98ce\u9669\u663e\u8457\u4e0b\u964d36.6%\uff08HR=0.634\uff09<sup>[1]<\/sup>\u3002<\/li>\n<li><b>\u5b89\u5168\u6027<\/b>\uff1a\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u8054\u5408\u6cbb\u7597\u7ec4\u4e0d\u826f\u53cd\u5e94\u8c31\u4e0e\u65e2\u5f80\u5355\u836f\u3001\u8054\u5408\u6cbb\u7597\u7684\u5b89\u5168\u6027\u6570\u636e\u4e00\u81f4\uff0c\u672a\u65b0\u589e\u672a\u77e5\u5b89\u5168\u98ce\u9669<sup>[1,2]<\/sup>\u3002\u5b89\u5168\u6027\u603b\u4f53\u53ef\u63a7<sup>[1]<\/sup>\u3002<\/li>\n<\/ul>\n<p class=\"prntal\"><b>SHR-1210-III-329\u7814\u7a76Leading 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class=\"prntal\">\u5bab\u9888\u764c\u662f\u4e25\u91cd\u5a01\u80c1\u5973\u6027\u5065\u5eb7\u7684\u6076\u6027\u80bf\u7624\uff0c\u5176\u53d1\u75c5\u7387\u4e0e\u6b7b\u4ea1\u7387\u5747\u5c45\u6211\u56fd\u5973\u6027\u751f\u6b96\u7cfb\u7edf\u80bf\u7624\u7684\u9996\u4f4d<sup>[3]<\/sup>\u3002\u5bf9\u4e8e\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u5bab\u9888\u764c\u60a3\u8005\uff0c\u4e00\u7ebf\u6cbb\u7597\u662f\u51b3\u5b9a\u5176\u751f\u5b58\u9884\u540e\u4e0e\u751f\u6d3b\u8d28\u91cf\u7684\u5173\u952e\u9636\u6bb5\u3002\u76ee\u524d\uff0c\u8be5\u75be\u75c5\u9886\u57df\u4ecd\u5b58\u5728\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u4e9f\u9700\u66f4\u4e3a\u6709\u6548\u7684\u6cbb\u7597\u65b9\u6848\u3002<\/p>\n<p 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class=\"prntal\">\u5361\u745e\u5229\u73e0\u5355\u6297\u662f\u6052\u745e\u533b\u836f\u81ea\u4e3b\u7814\u53d1\u7684\u4e00\u6b3e\u4eba\u6e90\u5316PD-1\u5355\u514b\u9686\u6297\u4f53\uff0c\u4e8e2019\u5e745\u6708\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\u4e0a\u5e02\u3002\u5361\u745e\u5229\u73e0\u5355\u6297\u5bf9PD-1\u5177\u6709\u9ad8\u4eb2\u548c\u529b\uff0c\u5728\u591a\u79cd\u5b9e\u4f53\u7624\u6cbb\u7597\u7814\u7a76\u4e2d\u53ef\u663e\u8457\u5ef6\u957f\u60a3\u8005\u603b\u751f\u5b58\u671f<sup>[5-7]<\/sup>\uff0c\u76ee\u524d\u5df2\u5728\u4e2d\u56fd\u83b7\u6279\u591a\u9879\u9002\u5e94\u75c7\uff0c\u6db5\u76d6\u80ba\u764c\u3001\u809d\u764c\u3001\u98df\u7ba1\u764c\u3001\u9f3b\u54bd\u764c\u4ee5\u53ca\u5bab\u9888\u764c\u4e94\u5927\u7624\u79cd\uff0c\u4e3a\u83b7\u6279\u9002\u5e94\u75c7\u548c\u8986\u76d6\u7624\u79cd\u6570\u91cf\u9886\u5148\u7684\u56fd\u4ea7PD-1\u4ea7\u54c1\u3002<\/p>\n<p class=\"prntal\"><b>\u5173\u4e8eSHR-1210-III-329\u7814\u7a76<\/b><\/p>\n<p class=\"prntal\">\u8fd9\u662f\u4e00\u9879\u82f9\u679c\u9178\u6cd5\u7c73\u66ff\u5c3c\u8054\u5408\u5361\u745e\u5229\u73e0\u5355\u6297\u5bf9\u6bd4\u542b\u94c2\u7c7b\u5316\u7597\u6cbb\u7597\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u5bab\u9888\u764c\u7684\u968f\u673a\u3001\u5f00\u653e\u3001\u5bf9\u7167\u3001\u591a\u4e2d\u5fc3\u7684III\u671f\u4e34\u5e8a\u7814\u7a76\uff0c\u5171\u7eb3\u5165443\u4f8b\u590d\u53d1\u6216\u8f6c\u79fb\u6027\u5bab\u9888\u764c\u60a3\u8005\uff0c\u57fa\u4e8ePD-L1\u8868\u8fbe\u72b6\u6001\uff08CPS\u22651 vs. CPS\uff1c1\uff09\u3001\u65e2\u5f80\u662f\u5426\u63a5\u53d7\u542b\u94c2\u6cbb\u7597\u8fdb\u884c\u5206\u5c42\uff0c\u4ee51:1\u6bd4\u4f8b\u5c06\u60a3\u8005\u968f\u673a\u5206\u5165\u6cd5\u7c73\u66ff\u5c3c\u8054\u5408\u5361\u745e\u5229\u73e0\u5355\u6297\u8054\u5408\u6cbb\u7597\u7ec4\u4e0e\u542b\u94c2\u5316\u7597\u7ec4\u3002\u5176\u4e2d\uff0cPD-L1\u8868\u8fbe\u9633\u6027\uff08CPS\u22651\uff09\u60a3\u8005\u5171412\u4f8b\uff0c\u5360\u603b\u5165\u7ec4\u4eba\u7fa4\u768493.0%\uff0c\u4e3a\u6838\u5fc3\u7597\u6548\u8bc4\u4ef7\u4eba\u7fa4\u3002<\/p>\n<p class=\"prntal\">\u7814\u7a76\u8bbe\u5b9a\u53cc\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\uff0c\u5373\u76f2\u6001\u72ec\u7acb\u5f71\u50cf\u8bc4\u5ba1\u59d4\u5458\u4f1a\uff08BICR\uff09\u8bc4\u4f30\u7684\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08PFS\uff09\u4e0e\u603b\u751f\u5b58\u671f\uff08OS\uff09\uff1b\u6b21\u8981\u7597\u6548\u7ec8\u70b9\u5305\u542b\u7814\u7a76\u8005\u8bc4\u4f30\u7684PFS\uff0c\u4ee5\u53caBICR\u3001\u7814\u7a76\u8005\u53cc\u7ef4\u5ea6\u8bc4\u4f30\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\uff08ORR\uff09\u3001\u75be\u75c5\u63a7\u5236\u7387\uff08DCR\uff09\u3001\u7f13\u89e3\u6301\u7eed\u65f6\u95f4\uff08DOR\uff09\uff0c\u5168\u9762\u7cfb\u7edf\u8bc4\u4f30\u65b9\u6848\u7684\u4e34\u5e8a\u83b7\u76ca\u3002<\/p>\n<p class=\"prntal\"><b>\u5173\u4e8e\u6052\u745e\u533b\u836f<\/b><\/p>\n<p class=\"prntal\">\u4f5c\u4e3a\u4e00\u5bb6\u4e13\u6ce8\u7814\u53d1\u3001\u751f\u4ea7\u53ca\u63a8\u5e7f\u9ad8\u54c1\u8d28\u836f\u7269\u7684\u521b\u65b0\u578b\u56fd\u9645\u5316\u5236\u836f\u4f01\u4e1a\uff0c\u6052\u745e\u533b\u836f\u59cb\u7ec8\u575a\u6301\u521b\u65b0\u4e0e\u56fd\u9645\u5316\u6218\u7565\u3002\u516c\u53f8\u7814\u53d1\u6295\u5165\u5360\u8425\u4e1a\u6536\u5165\u6bd4\u91cd\u8fde\u7eed\u591a\u5e74\u4fdd\u6301\u572825%\u4ee5\u4e0a\uff0c\u4f4d\u5c45\u884c\u4e1a\u524d\u5217\uff0c\u5e76\u4ee5\u6b64\u6784\u5efa\u8d77\u591a\u5143\u5316\u4e14\u7a33\u5065\u7684\u521b\u65b0\u4ea7\u54c1\u7ba1\u7ebf\u3002\u622a\u81f3\u76ee\u524d\uff0c\u5728\u4e2d\u56fd\u83b7\u627925\u6b3e1\u7c7b\u65b0\u836f\u30016\u6b3e2\u7c7b\u65b0\u836f\uff0c\u53e6\u6709100\u591a\u4e2a\u81ea\u4e3b\u521b\u65b0\u4ea7\u54c1\u6b63\u5728\u4e34\u5e8a\u5f00\u53d1\uff0c\u8d85400\u9879\u4e34\u5e8a\u8bd5\u9a8c\u5728\u56fd\u5185\u5916\u5f00\u5c55\u3002\u56fd\u9645\u5316\u65b9\u9762\uff0c\u6052\u745e\u533b\u836f\u4ea7\u54c1\u5df2\u572850\u591a\u4e2a\u56fd\u5bb6\u5b9e\u73b0\u5546\u4e1a\u5316\u3002\u516c\u53f8\u575a\u6301\u81ea\u4e3b\u7814\u53d1\u4e0e\u5f00\u653e\u5408\u4f5c\u5e76\u91cd\uff0c\u5728\u5185\u751f\u53d1\u5c55\u7684\u57fa\u7840\u4e0a\u7740\u529b\u52a0\u5f3a\u56fd\u9645\u5408\u4f5c\uff0c\u4e09\u5e74\u6765\u516c\u53f8\u5df2\u8fbe\u621013\u7b14\u521b\u65b0\u836f\u6d77\u5916\u4e1a\u52a1\u62d3\u5c55\u4ea4\u6613\u3002\u540c\u65f6\u516c\u53f8\u52a0\u901f\u81ea\u4e3b\u51fa\u6d77\u6b65\u4f10\uff0c\u6301\u7eed\u6253\u9020\u6d77\u5916\u56e2\u961f\uff0c\u63d0\u5347\u5168\u7403\u4e34\u5e8a\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u80fd\u529b\u3002<\/p>\n<\/p>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\"><\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">\u53c2\u8003\u6587\u732e\uff1a<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">1. \u6cd5\u7c73\u66ff\u5c3c\u8bf4\u660e\u4e66.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">2. Xia L, Zhang K, Tang Y, et al. Camrelizumab Plus Famitinib versus Camrelizumab Alone and Investigator&#8217;s Choice of Chemotherapy in Recurrent or Metastatic Cervical Cancer: A Randomized, Phase II Study. J Clin Oncol. Published online June 25, 2025.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">3. Han, B., et al. Cancer incidence and mortality in China, 2022. Journal of the National Cancer Center 4, 47-53 (2024).<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">4. \u5b50\u5bab\u9888\u764c\u6297\u8840\u7ba1\u751f\u6210\u836f\u7269\u4e34\u5e8a\u5e94\u7528\u6307\u5357(2023\u5e74\u7248). \u4e2d\u56fd\u5b9e\u7528\u5987\u79d1\u4e0e\u4ea7\u79d1\u6742\u5fd7,2023,39(12):1201-1209.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">5. Ren S, Chen J, Xu X, et al. Camrelizumab Plus Carboplatin and Paclitaxel as First-Line Treatment for Advanced Squamous NSCLC (CameL-Sq): A Phase 3 Trial[J]. J Thorac Oncol,2022,17(4):544-557.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">6. Zhou C, Chen G, Huang Y, et al. Camrelizumab plus carboplatin and pemetrexed versus chemotherapy alone in chemotherapy-na\u00efve patients with advanced non-squamous non-small-cell lung cancer (CameL): a randomized, open-label, multicentre, phase 3 trial[J]. Lancet Respir Med,2021,9(3):305-314.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">7. Zhou C, Chen G, Huang Y, et al. Camrelizumab Plus Carboplatin and Pemetrexed as First-Line Treatment for Advanced Nonsquamous NSCLC: Extended Follow-Up of CameL Phase 3 Trial[J]. J Thorac Oncol, 2023,18(5):628-639.<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"1\" class=\"prnbcc\">\n<tbody>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\"><\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">\u58f0\u660e\uff1a<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">1.\u672c\u65b0\u95fb\u65e8\u5728\u5206\u4eab\u7814\u53d1\u6ce8\u518c\u8fdb\u5c55\uff0c\u4ec5\u4f9b\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb\u53c2\u9605\uff0c\u975e\u5e7f\u544a\u7528\u9014\u3002<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">2.\u6052\u745e\u533b\u836f\u4e0d\u5bf9\u4efb\u4f55\u836f\u54c1\u548c\/\u6216\u9002\u5e94\u75c7\u4f5c\u63a8\u8350\u3002<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\">\n<p class=\"prnml4\"><span class=\"prnews_span\">3.\u672c\u65b0\u95fb\u4e2d\u6d89\u53ca\u7684\u4fe1\u606f\u4ec5\u4f9b\u53c2\u8003\uff0c\u8bf7\u9075\u4ece\u533b\u751f\u6216\u5176\u4ed6\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb\u7684\u610f\u89c1\u6216\u6307\u5bfc\u3002\u533b\u7597\u536b\u751f\u4e13\u4e1a\u4eba\u58eb\u4f5c\u51fa\u7684\u4efb\u4f55\u4e0e\u6cbb\u7597\u6709\u5173\u7684\u51b3\u5b9a\u5e94\u6839\u636e\u60a3\u8005\u7684\u5177\u4f53\u60c5\u51b5\u5e76\u9075\u7167\u836f\u54c1\u8bf4\u660e\u4e66\u3002<\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"prngen2\" colspan=\"1\" rowspan=\"1\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table><\/div>\n<p>&lt;<\/p>\n<p>p class=&#8221;wpematico_credit&#8221;><small>Powered by <a href=\"http:\/\/www.wpematico.com\" target=\"_blank\">WPeMatico<\/a><\/small><\/p>\n","protected":false},"excerpt":{"rendered":"<p>III\u671f\u7814\u7a76\u663e\u793a\uff0c\u827e\u6bd4\u7279\u00ae\uff08\u82f9\u679c\u9178\u6cd5\u7c73\u66ff\u5c3c\uff09\u8054\u5408\u827e\u745e\u5361\u00ae\uff08\u6ce8\u5c04\u7528\u5361\u745e\u5229\u73e0\u5355\u6297\uff09\u7ec4\u8f83\u5316\u7597\u7ec4\u5c55\u73b0\u51fa\u663e\u8457\u7684\u751f\u5b58\u83b7\u76ca\uff1a [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":5825,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[410],"tags":[],"class_list":["post-15098","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-reprint"],"_links":{"self":[{"href":"https:\/\/xiaguangshe.com\/en\/wp-json\/wp\/v2\/posts\/15098","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/xiaguangshe.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/xiaguangshe.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/xiaguangshe.com\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/xiaguangshe.com\/en\/wp-json\/wp\/v2\/comments?post=15098"}],"version-history":[{"count":0,"href":"https:\/\/xiaguangshe.com\/en\/wp-json\/wp\/v2\/posts\/15098\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/xiaguangshe.com\/en\/wp-json\/wp\/v2\/media\/5825"}],"wp:attachment":[{"href":"https:\/\/xiaguangshe.com\/en\/wp-json\/wp\/v2\/media?parent=15098"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/xiaguangshe.com\/en\/wp-json\/wp\/v2\/categories?post=15098"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/xiaguangshe.com\/en\/wp-json\/wp\/v2\/tags?post=15098"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}